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KMID : 0377519750010010067
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Chung-Ang Journal of Medicine
1975 Volume.1 No. 1 p.67 ~ p.76
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Morphological Study of Renal Juxtaglomerular Cell - Intracysternal Granules in Rough Surfaced Endoplasmic Reticulum and Granules in Parietal Cells of Bowman’s Capsule
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Rah Bong-Jin
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Abstract
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The renal tissues of mice of Swiss-Webster strain having been induced hyperactivity by adrenalectomy were fixed with 2.3% glutaraldehyde in 45mM cacodylate buffer and postfixed with cold 1% osmium tetroxide in 45mM cacodylate buffer, and then embedded in Epon 812 for electron microscopic study. During the previous experiment the unusual specific features of the juxtaglomerular cells of experimental animals No. 94 and No. 87 were observed, and then discussed through wide references published so far. 1. Animal No. 94 belonged to the group survived for one week after adrenalectomy and sacrificed at thirty minutes after cobalt nitrate injection. One of the juxtaglomerular cells in the media of the afferent arteriole showing markedly distended rough surfaced endoplasmic reticulum in which electron dense round granules without membrane was observed. 2. Animal No. 87 belonged to the group survived for four weeks after adrenalectomy and sacrificed at two hours after injection of cobalt nitrate. Some cells composing the parietal layer showed large round electron dense granules but small amount of free ribosomes and rough surfaced endoplasmic reticulum.
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